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248 In CML, mitochondrial and nuclear forms of STAT3 mediate TKI resistance through metabolic rewiring
Diez-Alarcia R, Yez-Prez V, Muneta-Arrate I, Arrasate S, Lete E, Meana JJ, Gonzlez-Daz H
Lactate regulates cell cycle by remodelling the anaphase promoting complex
Akkermansia muciniphila colonization in the gut is inversely associated with obesity, diabetes, metabolic syndrome, and low-grade chronic inflammation
The effects of MVs treatment on wound appearance The size of the wound area in the experimental groups during 18-days was calculated using software AxioVision Rel 4.8.2 (Fig
Contributing factors include: reduced nutritional intake (proteins, essential amino acids, competition between amino acid transporters, vitamin insufficiency [riboflavin: GSSG reductase, nicotinic acid: NADPH, pyridoxine (B 6 ): SAMe pathway], mitochondrial dysfunction: ATP deficiency, down regulation SAMe synthase, oxidation of SAMe pathway enzymes, enhanced GSH utilization: conjugation reactions (toxins, drugs), and overwhelming oxidative challenge
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